Meld score calculator4/19/2023 Replication analyses were conducted in the All of Us Research Program. Primary analyses were conducted in Vanderbilt University Medical Center (VUMC)’s deidentified electronic health record system. Objective To use laboratory values stored in electronic health records to describe population-level sex differences in all MELD laboratory values (in healthy individuals and patients with liver disease) and propose a sex adjustment.ĭesign, Setting, and Participants A retrospective cohort study was conducted from March 2019 to April 2020 to evaluate sex differences in laboratory values in liver transplant patients, patients with liver disease who did not undergo transplant, and healthy controls. During the MELD era, sex disparities in liver transplant have increased and there are no modifications to MELD based on sex. Importance Liver allocation is determined by the model for end-stage liver disease (MELD), a scoring system based on 4 laboratory measurements. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience. ![]()
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